Efficient estimation of the maximum metabolic productivity of batch systems

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Efficient estimation of the maximum metabolic productivity of batch systems

BACKGROUND Production of chemicals from engineered organisms in a batch culture involves an inherent trade-off between productivity, yield, and titer. Existing strategies for strain design typically focus on designing mutations that achieve the highest yield possible while maintaining growth viability. While these methods are computationally tractable, an optimum productivity could be achieved ...

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ژورنال

عنوان ژورنال: Biotechnology for Biofuels

سال: 2017

ISSN: 1754-6834

DOI: 10.1186/s13068-017-0709-0